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Flugestone acetate

Flugestone acetate (FGA), sold under the brand name Cronolone among others, is a progestin medication which is used in veterinary medicine.

Uses



Veterinary

FGA is used as an intravaginal sponge preparation to synchronize estrus in ewes and goats.

Chemistry

FGA, also known as 17α-acetoxy-9α-fluoro-11β-hydroxyprogesterone or as 17α-acetoxy-9α-fluoro-11β-hydroxypregn-4-ene-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone and 17α-hydroxyprogesterone. It is the C17α acetate ester of flugestone.

History

FGA was developed and marketed by G.D. Searle & Company in the 1960s.

Society and culture



Generic names

Flugestone acetate is the generic name of the drug and its and , while flurogestone acetate is its . Flugestone is the and of the unesterified free alcohol form. FGA is also known by its developmental code names NSC-65411 and SC-9880.

Brand names

FGA is or has been marketed under the brand names Chronogest, Chrono-Gest, Crono-Gest, Cronolone, Gyncro-Mate, Ova-Gest, Ovakron, Synchro-Mate, Syncro Part, and Syncropart.

Availability

FGA is marketed for veterinary use in Australia, France, Ireland, Israel, Italy, the Netherlands, South Africa, and the United Kingdom.